Hives, also known as urticaria, are a common skin reaction characterized by itchy welts. While they can be caused by allergies, certain diseases can also trigger hives in adults. This blog post aims to provide a detailed look at various diseases that are known to cause hives, helping adults identify potential underlying conditions and seek appropriate treatment.

1. Overview of Hives in Adults

Hives are red, raised, and often itchy welts that appear on the skin. They can vary in size and shape and may appear anywhere on the body. While hives are commonly associated with allergic reactions, they can also be a symptom of various diseases, particularly in adults.

2. Autoimmune Diseases and Hives

Autoimmune diseases, where the immune system mistakenly attacks the body’s own tissues, can lead to hives. Conditions like lupus, rheumatoid arthritis, and Sjögren’s syndrome are known to cause hives as one of their symptoms.

3. Infections Leading to Hives

Certain infections can also trigger hives. Viral infections, such as hepatitis, HIV, and Epstein-Barr virus, are known to cause hives in some adults. Bacterial infections, including urinary tract infections and strep throat, and parasitic infections can also lead to hives.

4. Endocrine Disorders and Hives

Endocrine disorders that affect hormone levels can trigger hives. Thyroid diseases, such as hyperthyroidism and hypothyroidism, are common examples. Additionally, diabetes and hormonal imbalances may also be linked to the occurrence of hives.

5. Gastrointestinal Diseases

Gastrointestinal disorders, including celiac disease and inflammatory bowel diseases like Crohn’s disease and ulcerative colitis, have been associated with hives. These conditions can cause immune system responses that manifest as skin reactions.

6. Other Diseases and Conditions

Other conditions, such as chronic infections, certain cancers, and blood diseases, can also lead to hives. It’s important to note that hives can sometimes be idiopathic, meaning no specific cause can be identified.


Understanding the diseases that can cause hives in adults is crucial for effective diagnosis and treatment. If you’re experiencing hives, it’s important to consult with a healthcare professional to determine if an underlying disease is the cause and to receive appropriate treatment.


Q: Can stress cause hives in adults?

A: Yes, stress can trigger hives in some adults, although it’s not considered a disease.

Q: Are hives always a sign of an underlying disease?

A: Not always. Hives can be caused by allergies, environmental factors, or idiopathic reasons, without any underlying disease.

Q: How are hives related to diseases treated?

A: Treatment focuses on managing the underlying disease and may include antihistamines to relieve hives.