Lactose intolerance, also called lactase deficiency, is the inability to completely digest milk sugar (lactose). Lactose intolerance is not usually dangerous, but its symptoms are unpleasant enough to persuade people with lactase deficiency not to consume dairy products.

The Right Reason

The cause of lactose intolerance is the lack of lactase, an enzyme produced by the lining of the small intestine. Lactase breaks down lactose so that it can be absorbed into the bloodstream. Lactase deficiency leads to the inability to break down and absorb sugar from milk.

Some people are convinced that they suffer from lactose intolerance, but in fact the digestion of lactose is done under normal conditions. Others have low lactase levels and still do not suffer from lactose intolerance. Only in the case of people with low lactase levels and symptoms is the diagnosis of lactose intolerance made.

The symptoms of lactose intolerance can be controlled with a diet that limits lactose intake without eliminating calcium and with nutritional supplements. The creation of NMN happens to be the intermediate step for the NAD +. In simpler words, the higher the NMN is, the higher is the level of NAD+. Choosing the right nmn powder manufacturer is important in this case.

Causes and pathogenesis

The osmotic load that occurs with the accumulation of lactose in the intestinal lumen causes increased secretion of fluids and electrolytes until the osmotic balance is reached. Intestinal dilation is caused by accelerated transit induced by osmosis, which increases the degree of maldigestion .In the intestine, unabsorbed lactose is fermented by colonic bacteria to short-chain fatty acids and free hydrogen. The combination of fluid, accelerated intestinal transit and hydrogen causes gastrointestinal symptoms.

Lactase deficiency can occur in three situations:

  • Congenital lactose intolerance
  • Secondary intolerance
  • Primary intolerance.

Congenital lactose intolerance involves the absence of the enzyme lactase from birth, due to a mutation in the gene responsible for coding lactase. It is a very rare form of deficiency, and symptoms begin immediately after birth.

Primary intolerance develops during childhood and persists into adulthood, it is a form of hypolactasia – the enzyme is found in small amounts. This decrease in lactase levels is genetically programmed in certain ethnic groups.

Signs and symptoms

The severity of symptoms of lactose intolerance varies from person to person, due to the different amount of lactose ingested and lactase deficiency. Common symptoms are gastrointestinal, diarrhea, abdominal pain, flatulence and less often bloating, hydro-aerial noises and nausea. They appear 30 minutes to two hours after a meal or after drinking lactose. Most often the consumption of milk determines the clinical manifestations, and in mild cases stopping it stops the symptoms.

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